Vitamin D

Vitamin D kdorfman Fri, 04/22/2022 - 17:53

Thermo Scientific B22524.03



MW = 384.65

Solubility (from Cayman Chemical)

solvent mg/mL = mM
ethanol 30 ~78 mM
DMSO 3 ~ 7.8 mM
DMF 25 ~65 mM

Stock solution: 29 mg/mL (~75 mM) in ethanol

General Description (from Thermo Scientific)

  • Vitamin D3 is a steroid hormone generated in the skin when the 7-dehydrocholesterol interacts with ultraviolet irradiation. It can also be found in several types of food for daily intake.
  • Vitamin D3 binds to vitamin D receptors, thus modulating gene expression


  • In in vivo studies, vitamin D3 has been implicated in the maintenance of blood calcium and phosphorus levels, bone metabolism, metabolic functions, and transcription regulation
  • It modulates the proliferation and differentiation of both normal and cancer cells
  • It presents in vitro antiproliferative and antimetastatic activities on breast, colon, and prostate cancer cells